Filtration ensures that biologics—like therapeutic proteins, antibodies, and vaccines—are safe, pure, and effective. Each filter is chosen based on the size, charge, and chemistry of what needs to be removed or retained. Effective filtration processes, including careful filter selection, integrity testing, and monitoring for turbidity and filter breakthrough, are essential for ensuring the quality, safety, and regulatory compliance of pharmaceutical products. Filter breakthrough occurs when a filter fails to adequately remove particles or microorganisms from a solution, allowing them to pass through into the filtrate.
Turbidity can be an early indicator of filter breakthrough, particularly in-depth filters that are susceptible to turbidity breakthrough. Monitoring turbidity with CANTY’s high resolution CCD/CMOS image sensors can signal unwanted particles in the filtrate caused by the contamination. This real-time analysis can prevent wasted time and material, and aid in producing high-quality, safe, and effective products.