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CENTRIFUGE CAMERA CONTROL
A camera light combination system is mounted to the centrifuge using the CANTY angled mounting plate. This allows for continuous monitoring from the control room, of initial product filling, the various washing and spinning cycles, and product discharge, therefore enabling greater operator control and efficient identification of any process issues. In the control room, the Vector™ image processing computer will analyze this view and provide a 4-20mA or OPC output of fill level, filtering level, and a separate cake (solids) detection signal. The level control allows for consistent batching to the centrifuge. The cake detection 4-20mA or OPC output signal provides for immediate detection of solids, which prevent the cake from cracking. This means higher product yield due to fewer washes, and ultimately better product quality.
CENTRIFUGE
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CRYSTALLIZATION
Manual monitoring of a crystallization process is done through the use of the CANTY Fuseview™ and Fiber Optic Lighting System, providing the operator with light and sight on one vessel connection, saving space, and also ensuring optimum illumination of the area which the operator is viewing. Remote process monitoring is possible through the use of a microscopic camera system to allow the user to view the growth of the crystals. The CANTY range combines CANTY’s fused glass and lighting technologies to provide an unrivaled continuous view from initial nucleation, allowing for early problem detection (eg. secondary seeding) and reaction. CANTYVISION™ image analysis software allows for particle size and shape characterization during the initial stages of crystal growth (up to 5% concentration), while the remote view is continuous throughout the process.
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CRYSTALSCOPE PAT PARTICLE SIZING SYSTEM
.7 um – 680 um Particle size analysis range in a reactor for monitoring crystal size in real time from nucleation to full growth. 2D results with no need for multiple probes
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LIQUID PARTICLE SIZE ANALYZERS
CANTY particle sizing analyzers have been engineered to offer the user a means by which a liquid is analyzed while under varying pressures, temperatures and flow rates. It offers sample or continuous, microscopic, non-destructive viewing and provides particle size analysis with two dimensional results when used in conjunction with the CantyVisionClient™ Software. The vision system, with integral lighting, features precision optics designed to enhance the image prior to display or analysis. The analyzer utilizes a high resolution / high speed image sensor coupled to a microscopic lens system. The system offers zoom and focus ability, variable lighting, and multiple objective lens packages to cover a range of sizes. CANTY particle sizing systems feature a FUSEVIEW glass window that acts as a product contact barrier. Our unique fused glass windows far exceed all other glass windows in safety and performance allowing for high pressure ratings.
CRYSTALLIZATION
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FILTER DRYER / NUTSCHE
Stop washing product away! Monitoring the entire filter drying process will yield higher production results. Using the CANTY light and FuseView will assist operators looking into the dryer by using the brightest net light output and the largest view in the industry. The CANTY camera and light combo can be used to control and monitor level control and cake detection. By using the CANTY system it will eliminate over drying of the cake.
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FILTER DRYER CONTROL SYSTEM
Features:
- Avoid cracked cake surface
- Optimize washing cycles
- Visual verification
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HYL 52 SANITARY LED LIGHTING SYSTEM
**New LED Lighting Systems** The HYL 52 LED lighting system is designed to illuminate bio reactors, fermentors and sanitary vessels. The HYL 52 light is a fused glass light which provides a high intensity, cold light source to allow the process to be viewed under a true white light (5000° K color temperature) while adding no heat to the process, which would cause product bake-on. The HYL 52 LED lighting package provides a compact, cost effective, maintenance free lighting system to meet all of your sanitary process needs. No more changing bulbs!
FILTER DRYER / NUTSCHE
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BIOCAM™ SANITARY PROCESS CAMERA
The CANTY BioCam™ is uniquely qualified to view inside your fermenters and bioreactors and provides a continual control signal allowing the user to meter in antifoam. The BioCam™ is an Ethernet based imaging system which connects to the CANTY VCM™ image processor that determines the percentage of foam on the surface of the liquid. The foam control function allows for significant savings of antifoam, improves process performance in cell culture growth and eliminates the need for additional antifoam fluids in purification. The all in-one design is both compact and sanitary and unlike its predecessors requires no additional external power supply for operation. A built in heater eliminates condensation from forming on the glass and provides for a clear image at all times. Coupled with CantyVision™ software, the BioCam™ can be used for full control via OPC or 4-20mA.
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LABCAM™ LAB GLASS VESSEL CAMERA & LOFT ENCLOSURE
The CANTY LabCam™ is uniquely qualified to view inside your glass lab fermenters and bioreactors and provides a continual control signal allowing the user to meter in antifoam. The LabCam™ is an Ethernet based imaging system which connects to the CANTY VCM™ image processor that determines the percentage of foam on the surface of the liquid. The foam control function allows for significant savings of antifoam, improves process performance in cell culture growth and eliminates the need for additional antifoam fluids in purification.
- Non-Contact foam & level monitoring and control
- Able to use on any size Bench-Top Bioreactor
- Correlates to markings / ruler on side of vessel
- Able to record continuous video feed or batches
- Remote viewing allows for vessel to be run dark
- Ease of use – multiple configurations and easily movable equipment
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NON-CONTACT LEVEL & FOAM CONTROL
CANTY Camera & Light Vision Systems are a patented design to view and illuminate the inside of a pressure or process vessel through a single connection. There is no need for multiple ports! CANTY can supply an integrally mounted camera and light (optional) in flanged, sanitary or NPT threaded process connections. CANTY fused glass technology provides a safe, high pressure, hermetic fused glass barrier between the process and the camera electronics.
The key to CANTY Camera & Light Vision Systems is the CANTY LED Light. CANTY uses fiber optic light guides to focus cool, effective light into a process or pressure vessel. Cool light eliminates product bake-on, adding no heat to the process. Fiber optic light guides deliver the maximum amount of light into the tank. The resulting live, remote image from a CANTY Camera & Light Vision System is unparalleled!
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PROCAM™ SANITARY PROCESS CAMERA
The CANTY ProCam™ is a process camera engineered and designed for sanitary applications. The ProCam™ combines the latest in LED lighting with Ethernet camera technology in a streamlined package.
TA11500-1099
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S.U.EXTERNAL BIOCAM™ Sanitary Process Camera
The single use vessel level system from CANTY allows operators to track the level inside a single use container by way of a camera, allowing for non-contact visual verification of the level. CantyVision™ software can output via 4-20mA or OPC to a PLC or DCS for complete control. The system utilizes the CANTY LED light with fiber optic bundle so the any size bag or container can be accommodated using the same system. The LED light is a cold white light with no heat transfer to the process so zero effect on the process conditions. Multiple control points can be set to alarm at various stages in the process.
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S.U.BIOCAM™ SANITARY PROCESS CAMERA
The CANTY S.U.BioCam™ is a process camera engineered and designed for sanitary applications. The S.U.BioCam™ combines the latest in LED lighting with Ethernet camera technology in a streamlined package. The camera utilizes built-in strobe LED light that has been optimized to run efficiently as to not obstruct photosensitive processes. Easy change disposable front caps for each process. Coupled with CantyVision™ software, the S.U.BioCam™ can be used for full control via OPC or 4-20mA.
FOAM & LEVEL DETECTION
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MINI INFLOW
Canty Mini Inflow analyzers utilize the latest in visible-spectrum microscopic imaging technology. Canty’s Gigabit Ethernet cameras, microscopic lenses, trademark fused glass, LED cool lighting systems, and proprietary CANTYVISION Intelligent Analysis software combine to provide the very best in real time analysis of particle concentration & size and shape distributions.
Mini Cell, Minicell
PARTICLE ANALYSIS / COUNT
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SPRAY DRYING
CANTY Spray Dryer Monitoring Systems are vision based, industrial camera / light combinations used to view spray nozzle patterns in real time. This allows operators to see changes in the profile of the spray pattern, and detect clogging before it becomes a problem. Operators can easily view for product build-up before there is a chance for fire. This Vision System can be automated by the CANTY Vector™ Image Processor to measure the size and shape of the spray pattern profile. 4-2mA or OPC alarms can then be sent to the control system if nozzles clog or the spray pattern changes.
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SPRAY DRYER CAMERA
CANTY Spray Dryer Monitoring Vision System can be fully automated by utilizing CANTY VISON™ software to measure the size and shape of the spray pattern profile. OPC UA Modbus or 4-20mA alarms can then be sent to the control system if nozzles clog or the spray pattern changes.
SPRAY DRYER
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LAB – SOLIDSIZER
The CANTY SolidSizer™ is a vision-based sensor used with the CANTY Vector System image processor for dry particle size measurement in a laboratory environment. The CantyVision™ Software accurately measures multiple aspects of the particles from area / perimeter / minor and major axis / etc. In comparison to a sieve which measures only minor axis the CantyVision™ software can correlate directly to a sieve so the customer does not have to change any QC documents. The SolidSizer™ can correlate within 2% of a sieve. A typical sieve analysis takes anywhere from 20-30 minutes including cleaning and setup for a 70-100 gram sample. On the SolidSizer™ that same sample takes less than 2 minutes. Also multiple screen distributions can be setup to accommodate multiple customers or areas in the process, hence eliminating the need for multiple runs on the same sand for different size distributions. After correlating to current methods of minor axis, customers find benefit in comparing minor axis to major axis and comparing shape factors. Reduce lab time and make sure production samples are not skipped over due to lack of sample time available!
VOLUME FLOW
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SINGLE USE PARTICLE ANALYZER
The CANTY SINGLEFLOW™ has been engineered to analyze small volume samples for particle size, shape and concentration in single use systems. The SINGLEFLOW™ easily converts from a lab unit to allow for continuous sampling in-line using sanitary Tri-Clamp™ connections. It offers microscopic, non-destructive viewing and provides particle size analysis with two dimensional results when used in conjunction with the CantyVisionClient™ Software. The vision system, with integral lighting, features precision optics designed to enhance the image prior to display or analysis. The image sensor is a high resolution / high speed CCD camera coupled to a microscopic lens system. The system offers zoom and focus ability, variable lighting, and disposable lens packages. The SINGLEFLOW™ features single use windows as the flush product contact barrier which ensures laminar flow & eliminates pockets for potential product build-up. Sizing down to 0.7 micron is possible with the high magnification optics and high intensity light source. A variety of pharmaceutical process need to be monitored and analyzed real time. This allows engineers and operators to view inside the process and give real-time results with visual verification.
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WFI – INFLOW™
The Canty Inflow™ is designed to be installed in-line to monitor WFI so the manufacture can have longer run times and can verify constant compliance with the USP. CANTY can output the particle concentration continuously so that if an upset does occur the operators are aware of it and take samples to the lab for further testing. What’s more, CANTY’s unique vision-based system allows for differentiation between particles and gas bubbles. Visual verification is provided and 4-20mA signals or OPC can be used to alarm to an upset condition.
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WFI – WATER FOR INJECTION
In Water for Injection (WFI) or Sterile Water applications, it is vital to measure and quantify the amount of foreign particles such as solids, rouge, droplets, or biofilm in a given volume to ensure the product meets certain purification standards. USP 788 / 1788 is the accepted set of guidelines for testing and concentration limits for particulate matter in injectables.
The CANTY InFlow™ analyzer utilizes dynamic imaging technology that measures the solids, droplets, gas, and any foreign materials, passing through an inline flow cell. Analyzing these particles continuously produces particle count and concentration data which can better inform decisions for downstream purification or upstream process control, as well as ensuring guideline compliance.
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BIOFILM
In pharmaceutical water systems, particularly WFI (Water for Injection) loops, biofilms pose a significant risk of contamination. Biofilms are essentially communities of microorganisms that attach to surfaces and create a protective matrix, making them difficult to remove and potentially leading to issues with product quality and safety. The CANTY INFLOW™ monitors water quality through particle analysis which is necessary to identify those microorganisms and address potential issues early on.
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ROUGING
Rouging in WFI (Water for Injection) systems refers to the formation of reddish-brown to dark violet iron deposits on the interior surfaces of stainless steel equipment, particularly in pharmaceutical and biotech industries. This phenomenon is a type of corrosion and is primarily caused by the oxidation of iron in the stainless steel, especially in the presence of hot WFI (above 60°C). Rouge can detach from the surfaces and contaminate the WFI, potentially affecting the quality and safety of pharmaceutical products. The CANTY InFlow™ detects these particles in real time, quantifying the amount of rouge being generated, providing an objective measure of system performance.